what happens if you drop a numerical varible in the summary table to replace

Introduction

The tbl_summary() function calculates descriptive statistics for continuous, categorical, and dichotomous variables in R, and presents the results in a cute, customizable summary table ready for publication (for example, Table i or demographic tables).

This vignette will walk a reader through the tbl_summary() office, and the various functions available to modify and make additions to an existing table summary object.

Setup

Before going through the tutorial, install and load {gtsummary}.

Example information set

Nosotros'll be using the trial data fix throughout this instance.

  • This set contains data from 200 patients who received ane of 2 types of chemotherapy (Drug A or Drug B). The outcomes are tumor response and decease.

  • Each variable in the data frame has been assigned an attribute label (i.due east.attr(trial$trt, "label") == "Chemotherapy Treatment") with the labelled package. These labels are displayed in the {gtsummary} output table by default. Using {gtsummary} on a data frame without labels will only impress variable names in identify of variable labels; there is as well an choice to add labels later.

Variable Class Label

trt

grapheme Chemotherapy Handling

historic period

numeric Age

marker

numeric Marker Level (ng/mL)

stage

factor T Stage

course

gene Grade

response

integer Tumor Response

decease

integer Patient Died

ttdeath

numeric Months to Death/Censor
Includes mix of continuous, dichotomous, and categorical variables
                                  head                  (                  trial                  )                  #>                    # A tibble: 6 × 8                                    #>   trt      age mark phase course response death ttdeath                  #>                    <chr>                    <dbl>                    <dbl>                    <fct>                    <fct>                    <int>                    <int>                    <dbl>                                    #>                    one                    Drug A    23  0.sixteen  T1    2           0     0    24                                    #>                    2                    Drug B     9  one.11  T2    I            one     0    24                                    #>                    3                    Drug A    31  0.277 T1    Two           0     0    24                                    #>                    4                    Drug A                    NA                    2.07  T3    Three          1     one    17.6                  #>                    5                    Drug A    51  2.77  T4    III          1     1    16.four                  #>                    6                    Drug B    39  0.613 T4    I            0     1    15.6                              

For brevity, in this tutorial we'll apply a subset of the variables from the trial data set.

Basic Usage

The default output from tbl_summary() is meant to be publication ready.

Let's outset by creating a table of summary statistics from the trial data ready. The tbl_summary() function tin take, at minimum, a data frame as the only input, and returns descriptive statistics for each column in the data frame.

Characteristic Northward = 200 ane
Chemotherapy Treatment
Drug A 98 (49%)
Drug B 102 (51%)
Historic period 47 (38, 57)
Unknown eleven
Grade
I 68 (34%)
II 68 (34%)
III 64 (32%)

i n (%); Median (IQR)

Note the sensible defaults with this bones usage; each of the defaults may be customized.

  • Variable types are automatically detected so that appropriate descriptive statistics are calculated.

  • Characterization attributes from the data set are automatically printed.

  • Missing values are listed as "Unknown" in the table.

  • Variable levels are indented and footnotes are added.

For this study data the summary statistics should be dissever by treatment group, which can be done past using the past= argument. To compare two or more groups, include add_p() with the function phone call, which detects variable type and uses an appropriate statistical examination.

Feature Drug A, N = 98one Drug B, N = 1021 p-value 2
Historic period 46 (37, 59) 48 (39, 56) 0.7
Unknown 7 4
Grade 0.9
I 35 (36%) 33 (32%)
II 32 (33%) 36 (35%)
III 31 (32%) 33 (32%)

i Median (IQR); n (%)

2 Wilcoxon rank sum test; Pearson's Chi-squared test

Customize Output

There are four primary means to customize the output of the summary table.

  1. Apply tbl_summary() function arguments
  2. Add additional data/information to a summary table with add_*() functions
  3. Modify summary table appearance with the {gtsummary} functions
  4. Modify tabular array appearance with {gt} package functions

Modifying tbl_summary() function arguments

The tbl_summary() function includes many input options for modifying the advent.

Argument Description

characterization=

specify the variable labels printed in table

type=

specify the variable type (east.thousand. continuous, chiselled, etc.)

statistic=

change the summary statistics presented

digits=

number of digits the summary statistics will be rounded to

missing=

whether to brandish a row with the number of missing observations

missing_text=

text label for the missing number row

sort=

change the sorting of categorical levels past frequency

per centum=

print column, row, or cell percentages

include=

list of variables to include in summary table

Example modifying tbl_summary() arguments.

Characteristic Drug A, Due north = 981 Drug B, N = 102one
Historic period 47.01 (xiv.71) 47.45 (14.01)
(Missing) 7 4
Tumor Grade
I 35 / 98 (36%) 33 / 102 (32%)
II 32 / 98 (33%) 36 / 102 (35%)
Three 31 / 98 (32%) 33 / 102 (32%)

1 Hateful (SD); n / North (%)

There are multiple ways to specify the statistic= argument using a single formula, a listing of formulas, and a named list. The following table shows equivalent ways to specify the mean statistic for continuous variables age and marking. Whatsoever {gtsummary} office argument that accepts formulas will accept each of these variations.

Select with Helpers Select past Variable Name Select with Named List

all_continuous() ~ "{mean}"

c("age", "marker") ~ "{mean}"

list(age = "{hateful}", marker = "{mean}")

list(all_continuous() ~ "{hateful}")

c(age, marker) ~ "{hateful}"

list(c(age, marker) ~ "{hateful}")

{gtsummary} functions to add information

The {gtsummary} package has functions to adding information or statistics to tbl_summary() tables.

Function Description

add_p()

add together p-values to the output comparing values across groups

add_overall()

add a column with overall summary statistics

add_n()

add a column with N (or N missing) for each variable

add_difference()

add column for departure between two group, confidence interval, and p-value

add_stat_label()

add together label for the summary statistics shown in each row

add_stat()

generic function to add together a column with user-defined values

add_q()

add together a cavalcade of q values to control for multiple comparisons

{gtsummary} functions to format table

The {gtsummary} package comes with functions specifically made to alter and format summary tables.

Example adding tbl_summary()-family functions

Tabular array 1. Patient Characteristics
Variable Northward Overall, N = 2001 Handling Received p-value ii
Drug A, N = 981 Drug B, North = 1021
Historic period 189 47 (38, 57) 46 (37, 59) 48 (39, 56) 0.72
Unknown 11 vii 4
Grade 200 0.87
I 68 (34%) 35 (36%) 33 (32%)
2 68 (34%) 32 (33%) 36 (35%)
Three 64 (32%) 31 (32%) 33 (32%)

1 Median (IQR) or Frequency (%)

2 Wilcoxon rank sum test; Pearson's Chi-squared test

{gt} functions to format tabular array

The {gt} packet is packed with many great functions for modifying tabular array output—too many to list here. Review the package's website for a full listing.

To use the {gt} packet functions with {gtsummary} tables, the summary table must first be converted into a gt object. To this finish, employ the as_gt() role after modifications have been completed with {gtsummary} functions.

Characteristic Northward Drug A, N = 981 Drug B, North = 1021
Age 189 46 (37, 59) 48 (39, 56)
Form 200
I 35 (36%) 33 (32%)
2 32 (33%) 36 (35%)
III 31 (32%) 33 (32%)
This information is simulated

1 Median (IQR); north (%)

Select Helpers

There is flexibility in how you select variables for {gtsummary} arguments, which allows for many customization opportunities! For instance, if y'all want to prove age and the marking levels to 1 decimal identify in tbl_summary(), you can pass digits = c(age, marking) ~ i. The selecting input is flexible, and you may also pass quoted column names.

Going beyond typing out specific variables in your data set, yous tin use:

  1. All {tidyselect} helpers available throughout the tidyverse, such as starts_with(), contains(), and everything() (i.east. annihilation you can employ with the dplyr::select() part), tin can exist used with {gtsummary}.

  2. Additional {gtsummary} selectors that are included in the package to supplement tidyselect functions.

    • Summary blazon In that location are two primary ways to select variables by their summary type. This is useful, for example, when you lot wish to report the mean and standard deviation for all continuous variables: statistic = all_continuous() ~ "{hateful} ({sd})".

      Dichotomous variables are, by default, included with all_categorical().

Multi-line Continuous Summaries

Continuous variables may also exist summarized on multiple lines—a mutual format in some journals. To update the continuous variables to summarize on multiple lines, update the summary type to "continuous2" (for summaries on 2 or more lines).

Characteristic Drug A, N = 98 Drug B, N = 102 p-value i
Age 0.72
Due north 91 98
Median (IQR) 46 (37, 59) 48 (39, 56)
Range vi, 78 nine, 83

1 Wilcoxon rank sum test

Avant-garde Customization

The information in this department applies to all {gtsummary} objects.

The {gtsummary} tabular array has ii important internal objects:

Internal Object Clarification

.$table_body

data frame that is printed as the gtsummary output table

.$table_styling

contains instructions for styling .$table_body when printed

When you print output from the tbl_summary() role into the R panel or into an R markdown document, the .$table_body data frame is formatted using the instructions listed in .$table_styling. The default printer converts the {gtsummary} object to a {gt} object with as_gt() via a sequence of {gt} commands executed on .$table_body. Here's an instance of the beginning few calls saved with tbl_summary():

                                  tbl_summary                  (                  trial2                  )                  %>%                  as_gt                  (return_calls                  =                  Truthful                  )                  %>%                  caput                  (n                  =                  4                  )                  #> $gt                  #> gt::gt(information = x$table_body, groupname_col = Goose egg, explanation = Cypher)                  #>                                    #> $fmt_missing                  #> $fmt_missing[[i]]                  #> gt::fmt_missing(columns = gt::everything(), missing_text = "")                  #>                                    #>                                    #> $cols_align                  #> $cols_align[[ane]]                  #> gt::cols_align(columns = c("variable", "var_type", "var_label",                                    #> "row_type", "stat_0"), align = "center")                  #>                                    #> $cols_align[[2]]                  #> gt::cols_align(columns = "characterization", marshal = "left")                  #>                                    #>                                    #> $tab_style_indent                  #> $tab_style_indent[[1]]                  #> gt::tab_style(style = gt::cell_text(indent = gt::px(x), marshal = "left"),                                    #>     locations = gt::cells_body(columns = "label", rows = c(2L,                                    #>     3L, 5L, 7L, 8L, 9L)))                              

The {gt} functions are called in the order they appear, beginning with gt::gt().

If the user does not want a specific {gt} part to run (i.e. would like to modify default printing), whatever {gt} call can be excluded in the as_gt() part. In the case below, the default alignment is restored.

After the as_gt() function is run, additional formatting may be added to the table using {gt} functions. In the example below, a source notation is added to the table.

Feature Drug A, N = 981 Drug B, North = 102one
Age 46 (37, 59) 48 (39, 56)
Unknown 7 4
Grade
I 35 (36%) 33 (32%)
Two 32 (33%) 36 (35%)
3 31 (32%) 33 (32%)
This data is fake

1 Median (IQR); n (%)

Set Default Options with Themes

The {gtsummary} tbl_summary() part and the related functions have sensible defaults for rounding and presenting results. If you, still, would like to change the defaults there are a few options. The default options tin can be inverse using the {gtsummary} themes part set_gtsummary_theme(). The parcel includes prespecified themes, and you can also create your own. Themes can command baseline behavior, for example, how p-values and percentages are rounded, which statistics are presented in tbl_summary(), default statistical tests in add_p(), etc.

For details on creating a theme and setting personal defaults, review the themes vignette.

Survey Data

The {gtsummary} package likewise supports survey data (objects created with the {survey} package) via the tbl_svysummary() function. The syntax for tbl_svysummary() and tbl_summary() are nearly identical, and the examples to a higher place apply to survey summaries too.

To begin, install the {survey} bundle and load the apiclus1 information set.

                                  # loading the api data set                  data                  (                  api, packet                  =                  "survey"                  )                              

Before nosotros begin, nosotros convert the data frame to a survey object, registering the ID and weighting columns, and setting the finite population correction column.

                                  svy_apiclus1                  <-                  survey                  ::                  svydesign                  (                  id                  =                  ~                  dnum,      weights                  =                  ~                  pw,      information                  =                  apiclus1,      fpc                  =                  ~                  fpc                  )                              

After creating the survey object, nosotros can now summarize it similarly to a standard data frame using tbl_svysummary(). Like tbl_summary(), tbl_svysummary() accepts the by= argument and works with the add_p() and add_overall() functions.

It is not possible to pass custom functions to the statistic= argument of tbl_svysummary(). You must use one of the pre-defined summary statistic functions (e.g.{mean}, {median}) which leverage functions from the {survey} parcel to calculate weighted statistics.

                                  svy_apiclus1                  %>%                  tbl_svysummary                  (                  # stratify summary statistics by the "both" column                  past                  =                  both,                  # summarize a subset of the columns                  include                  =                  c                  (                  api00,                  api99,                  both                  ),                  # calculation labels to table                  label                  =                  list                  (                  api00                  ~                  "API in 2000",                  api99                  ~                  "API in 1999"                  )                  )                  %>%                  add_p                  (                  )                  %>%                  # comparing values by "both" column                  add_overall                  (                  )                  %>%                  # adding spanning header                  modify_spanning_header                  (                  c                  (                  "stat_1",                  "stat_2"                  )                  ~                  "**Met Both Targets**"                  )                              
Characteristic Overall, North = 6,1941 Met Both Targets p-value 2
No, N = 1,6921 Yeah, N = four,5021
API in 2000 652 (552, 718) 631 (556, 710) 654 (551, 722) 0.4
API in 1999 615 (512, 691) 632 (548, 698) 611 (497, 686) 0.2

1 Median (IQR)

2 Wilcoxon rank-sum test for complex survey samples

tbl_svysummary() can as well handle weighted survey data where each row represents several individuals:

Feature N = 2,201 ane
Age
Adult 2,092 (95%)
Child 109 (five.0%)
Survived 711 (32%)

ane n (%)

Cross Tables

Utilise tbl_cross() to compare two categorical variables in your data. tbl_cross() is a wrapper for tbl_summary() that:

  • Automatically adds a spanning header to your tabular array with the name or label of your comparison variable.
  • Uses percent = "cell" by default.
  • Adds row and cavalcade margin totals (customizable through the margin argument).
  • Displays missing data in both row and column variables (customizable through the missing argument).
Characteristic Chemotherapy Treatment Full p-value 1
Drug A Drug B
T Stage 0.nine
T1 28 (14%) 25 (12%) 53 (26%)
T2 25 (12%) 29 (14%) 54 (27%)
T3 22 (11%) 21 (10%) 43 (22%)
T4 23 (12%) 27 (fourteen%) fifty (25%)
Total 98 (49%) 102 (51%) 200 (100%)

1 Pearson's Chi-squared test

wardmoreats.blogspot.com

Source: https://www.danieldsjoberg.com/gtsummary/articles/tbl_summary.html

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